Hello and welcome to medical dialogues show. I am Dr Nandita Mohan and we mark World Sepsis Day every year on 13th September 2024. Sepsis is the common final pathway of all acute infections. It arises when the body’s response to an infection injures its own tissues and organs. It may lead to shock, multiple organ failure, and death, especially if not recognized early and treated promptly.To talk to us on this day today, we have Dr. Prachi Sathe, Director of the Department of Critical Care Medicine, Ruby Hall Clinic Pune, Maharashtra.Dr Prachi underwent training in U.K. at Birmingham and Sheffield in the area of Critical Care Medicine on a scholarship by Royal College of Physicians, Edinburg for overseas students. After returning from U.K., she started multi multi-disciplinary ICU at Ruby Hall Clinic (first of its kind in Pune). This ICU which started as a 4-bed unit is now 125 bedded unit treating about 1000s of critically ill patients per year. She is the Founder Member of Intensive Care Society of India a recognised Teacher for Fellowships and Diploma in Critical Care Medicine, She has participated in several International Clinical Trials and Research Initiatives and delivered several talks at National and International Conferences and Workshops. Here she shares her insights on:1. What makes neonates and older adults more susceptible to infections that can lead to sepsis compared to other age groups?2. What are the most common underlying conditions in older adults that predispose them to sepsis?3. What are the high-risk patient groups for developing sepsis?4. Is there a connection between cognitive decline or dementia in older adults and their higher risk of developing sepsis?