Girls given antibiotics during their first year of life, especially in the first three months, are more likely to enter puberty at an earlier age, according to research presented at the first Joint Congress between the European Society of Pediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE). The likelihood of early puberty was also higher among those exposed to a greater variety of antibiotic classes. The findings highlight the importance of using these medicines in infants appropriately and how early-life drug exposure could shape future health outcomes.